2. Isotope-Labeled Compounds
  3. Isotope-Labeled Steroids

Isotope-Labeled Steroids

Steroids are biologically active organic compounds with four rings arranged in a specific molecular configuration, three six-membered cyclohexane rings ( rings A, B and C ) and one five-member cyclopentane ring ( ring D). Steroid compounds mainly include sterols, bile acids and bile alcohols, steroid hormones, and steroid drugs etc. MedChemExpress ( MCE ) offers a broad range of Stable Isotope-Labeled Steroids which can be used as internal standards for the accurate quantitative GC/LC-MS analysis and involved in metabolomics.

Isotope-Labeled Steroids (362):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0324S
    Cholic acid-d4 116380-66-6 99.86%
    Cholic acid-d4 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-d<sub>4</sub>
  • HY-15331
    VD3-d6 118584-54-6 99.45%
    VD3-d6 (Vitamin D3-26,26,26,27,27,27-d6) is deuterated VD3. Compounds labeled with stable or radioactive isotopes can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    VD3-d<sub>6</sub>
  • HY-B1788S
    Taurocholic acid-d4 sodium 2410279-93-3 99.29%
    Taurocholic acid-d4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.
    Taurocholic acid-d<sub>4</sub> sodium
  • HY-18569S
    3-Indoleacetic acid-d5 76937-78-5 99.84%
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].
    3-Indoleacetic acid-d<sub>5</sub>
  • HY-B0141S1
    Estradiol-d4 66789-03-5 99.55%
    Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
    Estradiol-d<sub>4</sub>
  • HY-13771S1
    Ursodeoxycholic acid-13C 63296-46-8
    Ursodeoxycholic acid-13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].
    Ursodeoxycholic acid-<sup>13</sup>C
  • HY-76847S
    Chenodeoxycholic Acid-d4 99102-69-9 99.19%
    Chenodeoxycholic Acid-d4 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Chenodeoxycholic Acid-d<sub>4</sub>
  • HY-N0322S
    Cholesterol-d7 83199-47-7 98.29%
    Cholesterol-d7 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.
    Cholesterol-d<sub>7</sub>
  • HY-N0593S
    Deoxycholic acid-d4 112076-61-6 98.0%
    Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>4</sub>
  • HY-N7142S
    DL-Norepinephrine-d6 hydrochloride 1219803-04-9 99.88%
    DL-Norepinephrine-d6 (hydrochloride) is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial oxygen tension[1].
    DL-Norepinephrine-d<sub>6</sub> hydrochloride
  • HY-B0075S
    Melatonin-d4 66521-38-8
    Melatonin-d4 is deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4].
    Melatonin-d<sub>4</sub>
  • HY-B0172S
    Lithocholic acid-d4 83701-16-0 99.72%
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid[1].
    Lithocholic acid-d<sub>4</sub>
  • HY-13332
    Calcifediol-d6 78782-98-6 98.91%
    Calcifediol-d6 is the deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR ligand.
    Calcifediol-d<sub>6</sub>
  • HY-B1618S
    Corticosterone-d8 1271728-07-4 99.91%
    Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>8</sub>
  • HY-113293BS1
    Estrone sulfate-d4 sodium 285979-80-8 99.38%
    Estrone sulfate-d4 (sodium) is deuterium labeled Estrone sulfate (sodium). Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). strone sulfate can be used for the research of breast cancer[1][2].
    Estrone sulfate-d<sub>4</sub> sodium
  • HY-101952S
    Prostaglandin E2-d4 34210-10-1 ≥99.0%
    Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].
    Prostaglandin E2-d<sub>4</sub>
  • HY-15329
    Maxacalcitol-d6 99.63%
    Maxacalcitol-d66 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
    Maxacalcitol-d<sub>6</sub>
  • HY-N0324S2
    Cholic acid-13C 52886-36-9 ≥98.0%
    Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
    Cholic acid-<sup>13</sup>C
  • HY-15330
    Vitamin D2-d3 1217448-46-8 98.60%
    Vitamin D2-d3 (Ergocalciferol-d3) is the deuterium labeled vitamin D2.
    Vitamin D2-d<sub>3</sub>
  • HY-B1618S1
    Corticosterone-d4 2243253-91-8 99.17%
    Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
    Corticosterone-d<sub>4</sub>