2. Natural Products
  3. Plants Alkaloids
  4. Taxaceae Other Alkaloids
  5. Cephalotaxus harringtonia (Knight ex J.Forbes) K.Koch
  6. 5′-Des-O-methylharringtonine

5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia.

For research use only. We do not sell to patients.

5′-Des-O-methylharringtonine Chemical Structure

5′-Des-O-methylharringtonine Chemical Structure

CAS No. : 182325-73-1

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5′-Des-O-methylharringtonine Related Antibodies

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Description

5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 100 μM
Compound: HT1
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 68 hrs by MTS assay
Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth measured after 68 hrs by MTS assay
[PMID: 35148094]
HL-60 IC50
> 100 μM
Compound: HT1
Antiproliferative activity against human HL60 cells after 62 hrs by MTS assay
Antiproliferative activity against human HL60 cells after 62 hrs by MTS assay
[PMID: 29286665]
HL-60 IC50
> 100 μM
Compound: HT1
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth measured after 68 hrs by MTS assay
Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth measured after 68 hrs by MTS assay
[PMID: 35148094]
Molecular Weight

517.57

Formula

C27H35NO9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)(O)CC[C@](CC(O)=O)(O)C(O[C@H]1[C@]2([H])[C@]3(C=C1OC)N(CCC3)CCC4=CC(OCO5)=C5C=C42)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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5′-Des-O-methylharringtonine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5′-Des-O-methylharringtonine182325-73-1OthersInhibitorinhibitorinhibit

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