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  3. Isotope-Labeled Compounds
  4. 5-Hydroxyindole-3-acetic acid-d5

5-Hydroxyindole-3-acetic acid-d5 

Cat. No.: HY-W008253S2 Purity: 96.06%
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5-Hydroxyindole-3-acetic acid-d5is the deuterium labeled5-Hydroxyindole-3-acetic acid(HY-W008253). 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

For research use only. We do not sell to patients.

5-Hydroxyindole-3-acetic acid-d<sub>5</sub> Chemical Structure

5-Hydroxyindole-3-acetic acid-d5 Chemical Structure

CAS No. : 81587-11-3

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2500 μg USD 628 In-stock

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Based on 1 publication(s) in Google Scholar

Other Forms of 5-Hydroxyindole-3-acetic acid-d5:

5-Hydroxyindole-3-acetic acid-d5 Related Antibodies

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Description

5-Hydroxyindole-3-acetic acid-d5is the deuterium labeled5-Hydroxyindole-3-acetic acid(HY-W008253)[1]. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-Hydroxyindole-3-acetic acid-d5 Related Antibodies
Molecular Weight

196.21

Formula

C10H4D5NO3
CAS No.
Unlabeled CAS

54-16-0
Appearance

Solid

Color

White to off-white

SMILES

OC1=C([2H])C(C(C([2H])([2H])C(O)=O)=C([2H])N2)=C2C=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (509.66 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0966 mL 25.4829 mL 50.9658 mL
5 mM 1.0193 mL 5.0966 mL 10.1932 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.0966 mL 25.4829 mL 50.9658 mL 127.4145 mL
5 mM 1.0193 mL 5.0966 mL 10.1932 mL 25.4829 mL
10 mM 0.5097 mL 2.5483 mL 5.0966 mL 12.7415 mL
15 mM 0.3398 mL 1.6989 mL 3.3977 mL 8.4943 mL
20 mM 0.2548 mL 1.2741 mL 2.5483 mL 6.3707 mL
25 mM 0.2039 mL 1.0193 mL 2.0386 mL 5.0966 mL
30 mM 0.1699 mL 0.8494 mL 1.6989 mL 4.2472 mL
40 mM 0.1274 mL 0.6371 mL 1.2741 mL 3.1854 mL
50 mM 0.1019 mL 0.5097 mL 1.0193 mL 2.5483 mL
60 mM 0.0849 mL 0.4247 mL 0.8494 mL 2.1236 mL
80 mM 0.0637 mL 0.3185 mL 0.6371 mL 1.5927 mL
100 mM 0.0510 mL 0.2548 mL 0.5097 mL 1.2741 mL
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5-Hydroxyindole-3-acetic acid-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Hydroxyindole-3-acetic acid-d581587-11-3Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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