5-Iodo-A-85380 dihydrochloride (Synonyms: 5-I A-85380 dihydrochloride)

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5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with K_ds of 12 and 14 pM,respectively.

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5-Iodo-A-85380 dihydrochloride Chemical Structure

CAS No. : 1217837-17-6

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Description	5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with K_ds of 12 and 14 pM,respectively^[1].
Molecular Weight	363.02
Formula	C₉H₁₃Cl₂IN₂O
CAS No.	1217837-17-6
SMILES	IC1=CC(OC[C@@H]2CCN2)=CN=C1.[H]Cl.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Mukhin AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol. 2000 Mar;57(3):642-9. [Content Brief]

5-Iodo-A-85380 dihydrochloride Related Classifications

Neurological Disease

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C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Iodo-A-853801217837-17-65-I A-85380nAChRNicotinic acetylcholine receptorsnAChRs Ligandα4β2 nAChRsInhibitorinhibitorinhibit

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5-Iodo-A-85380 dihydrochloride (Synonyms: 5-I A-85380 dihydrochloride)

5-Iodo-A-85380 dihydrochloride Related Antibodies

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