2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. 5-Propargylamino-3'-azidomethyl-dCTP TEA

5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 17 in patent document WO2004018497A2. 5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a click chemistry reagent containing an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC).

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5-Propargylamino-3'-azidomethyl-dCTP TEA Chemical Structure

5-Propargylamino-3'-azidomethyl-dCTP TEA Chemical Structure

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1 mg USD 320 In-stock
5 mg USD 820 In-stock
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5-Propargylamino-3'-azidomethyl-dCTP TEA Related Antibodies

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Description

5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 17 in patent document WO2004018497A2. 5-Propargylamino-3'-azidomethyl-dCTP (TEA) is a click chemistry reagent containing an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC)[1].

Molecular Weight

909.19

Formula

C13H20N7O13P3.3.3C6H15N
Appearance

Solid

SMILES

O=C1N([C@H]2C[C@H](OCN=[N+]=[N-])[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N)=N1)C#CCN.CCN(CC)CC.[3.3]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (137.49 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0999 mL 5.4994 mL 10.9988 mL
5 mM 0.2200 mL 1.0999 mL 2.1998 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0999 mL 5.4994 mL 10.9988 mL 27.4970 mL
5 mM 0.2200 mL 1.0999 mL 2.1998 mL 5.4994 mL
10 mM 0.1100 mL 0.5499 mL 1.0999 mL 2.7497 mL
15 mM 0.0733 mL 0.3666 mL 0.7333 mL 1.8331 mL
20 mM 0.0550 mL 0.2750 mL 0.5499 mL 1.3749 mL
25 mM 0.0440 mL 0.2200 mL 0.4400 mL 1.0999 mL
30 mM 0.0367 mL 0.1833 mL 0.3666 mL 0.9166 mL
40 mM 0.0275 mL 0.1375 mL 0.2750 mL 0.6874 mL
50 mM 0.0220 mL 0.1100 mL 0.2200 mL 0.5499 mL
60 mM 0.0183 mL 0.0917 mL 0.1833 mL 0.4583 mL
80 mM 0.0137 mL 0.0687 mL 0.1375 mL 0.3437 mL
100 mM 0.0110 mL 0.0550 mL 0.1100 mL 0.2750 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Propargylamino-3'-azidomethyl-dCTP TEA Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Propargylamino-3'-azidomethyl-dCTPDNA/RNA SynthesisInhibitorinhibitorinhibit

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