5-Valine-angiotensin I

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5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone.

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5-Valine-angiotensin I Chemical Structure

CAS No. : 484-43-5

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Description	5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone^[1]^[2].
In Vitro	5-Valine-angiotensin I shows myotropic effect (muscle contraction) on isolated rat colon after nonspecific desensitization of receptors with acetylcholine^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 5-Valine-angiotensin I Related Antibodies
Molecular Weight	1282.45
Formula	C₆₁H₈₇N₁₇O₁₄
CAS No.	484-43-5
Sequence Shortening	DRVYVHPFHL
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (257 KB) Handling Instructions (2659 KB)
References	[1]. Hayashi Y, et al. Synthesis and specific pressor activity of [1-aspartic acid,5-valine,9-serine]angiotensin I ("fowl angiotensin I"). J Med Chem. 1977 Feb;20(2):315-6. [Content Brief] [2]. Myshlyakova, et al. Pharmacological characteristics of "active sites" of the angiotensin. Khimiko-Farmatsevticheskii Zhurnal, 1977, 11(7):6-11. [Russian]