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  6. 6,8-Diprenylgenistein

6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis .

For research use only. We do not sell to patients.

6,8-Diprenylgenistein Chemical Structure

6,8-Diprenylgenistein Chemical Structure

CAS No. : 51225-28-6

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6,8-Diprenylgenistein Related Antibodies

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Description

6,8-Diprenylgenistein is an isoflavone compound isolated from Cudrania tricuspidata. 6,8-Diprenylgenistein has antimicrobial and anti-obesity activity. 6,8-Diprenylgenistein inhibits the proliferation, migration and tubular formation of HLMEC induced by recombinant human vascular endothelial growth factor-A. 6,8-Diprenylgenistein can be used to study new therapeutic drugs for the prevention and treatment of oral cancer metastasis [1].

Cellular Effect
Cell Line Type Value Description References
MCF7 IC50
8.58 μM
Compound: 38
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
RAW264.7 IC50
19.2 μM
Compound: 10
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells by Griess assay
[PMID: 19113968]
SW480 IC50
8.08 μM
Compound: 38
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
[PMID: 28522265]
Molecular Weight

406.47

Formula

C25H26O5
CAS No.
SMILES

O=C1C(C2=CC=C(O)C=C2)=COC3=C(C/C=C(C)\C)C(O)=C(C/C=C(C)\C)C(O)=C13
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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6,8-Diprenylgenistein Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6,8-Diprenylgenistein51225-28-6Othersoral cancer6,8-diprenylgenisteinVEGF-A-induced lymphangiogenesissentinel lymph node metastasisInhibitorinhibitorinhibit

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