2. Metabolic Enzyme/Protease MAPK/ERK Pathway GPCR/G Protein
  3. Endogenous Metabolite Ras
  4. 6-T-GDP

6-T-GDP  (Synonyms: 6-Thioguanosine 5'-diphosphate)

Cat. No.: HY-134243
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6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of azathioprine. 6-T-GDP can reduce the transcription of inflammatory factors and the expression of cell adhesion molecules by inhibiting the activity of Rac1, thereby inhibiting the migration of leukocytes and the occurrence of tissue inflammation.

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6-T-GDP Chemical Structure

6-T-GDP Chemical Structure

CAS No. : 16541-19-8

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6-T-GDP Related Antibodies

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Description

6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of azathioprine. 6-T-GDP can reduce the transcription of inflammatory factors and the expression of cell adhesion molecules by inhibiting the activity of Rac1, thereby inhibiting the migration of leukocytes and the occurrence of tissue inflammation[1].

Molecular Weight

459.27

Formula

C10H15N5O10P2S
CAS No.
SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O[C@H]1N(C=N2)C3=C2C(NC(N)=N3)=S
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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6-T-GDP Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-T-GDP16541-19-86-Thioguanosine 5'-diphosphateEndogenous MetaboliteRasMetaboliteInflammationLeukocytesRac1Cell adhesion moleculeInhibitorinhibitorinhibit

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