7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (Synonyms: DEDA)

Cat. No.: HY-23909: FAQs
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7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A₂ (PLA₂) (IC₅₀ = 16 µM) and snake venom PLA₂ (IC₅₀ = 14 µM).

For research use only. We do not sell to patients.

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid Chemical Structure

CAS No. : 89560-01-0

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Description	7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A₂ (PLA₂) (IC₅₀ = 16 µM) and snake venom PLA₂ (IC₅₀ = 14 µM)^[1].
In Vitro	7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) has a significant effect on the βA(25-35)-stimulated response. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) reduces the formation of ROS^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid Related Antibodies
Molecular Weight	336.55
Formula	C₂₂H₄₀O₂
CAS No.	89560-01-0
SMILES	CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (261 KB) Handling Instructions (2659 KB)
References	[1]. Jannike M Andersen, et al. Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease. Neurochem Res. 2003 Feb;28(2):319-26. [Content Brief]

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid Related Classifications

Inflammation/Immunology

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid89560-01-0DEDAPhospholipaseROAPLA2phospholipaseβA(25-35)Inhibitorinhibitorinhibit

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