2. NF-κB Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. NF-κB PPAR
  4. 7,8-Didehydrocimigenol

7,8-Didehydrocimigenol is an active triterpenoid that can be isolated from Cimicifugae rhizoma. 7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibits NF-kB activity and phosphorylation of ERK1/2 and Akt, increases PPAR-γ expression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis.

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7,8-Didehydrocimigenol Chemical Structure

7,8-Didehydrocimigenol Chemical Structure

CAS No. : 150972-72-8

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7,8-Didehydrocimigenol Related Antibodies

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Description

7,8-Didehydrocimigenol is an active triterpenoid that can be isolated from Cimicifugae rhizoma. 7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibits NF-kB activity and phosphorylation of ERK1/2 and Akt, increases PPAR-γ expression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis[1].

Molecular Weight

486.68

Formula

C30H46O5
CAS No.
SMILES

C[C@]12C3=CC[C@](C(C)([C@H](CC4)O)C)([H])[C@]54[C@@]3(CC[C@@]1([C@]6([H])[C@@]7(O[C@@H]([C@H](O7)C(C)(O)C)C[C@H]6C)[C@@H]2O)C)C5
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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7,8-Didehydrocimigenol Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

7,8-Didehydrocimigenol150972-72-8NF-κBPPARNuclear factor-κBNuclear factor-kappaBPeroxisome proliferator-activated receptorstriterpenoidCimicifugae rhizomeTNF-αVCAM-1PPAR-γInhibitorinhibitorinhibit

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