2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 7-Deazaguanosine

7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

7-Deazaguanosine Chemical Structure

7-Deazaguanosine Chemical Structure

CAS No. : 62160-23-0

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Based on 1 publication(s) in Google Scholar

7-Deazaguanosine Related Antibodies

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Description

7-Deazaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Cellular Effect
Cell Line Type Value Description References
MRC5 EC50
> 64 μM
Compound: 18
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence assay
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence assay
[PMID: 31931339]
Molecular Weight

282.25

Formula

C11H14N4O5
CAS No.
SMILES

O[C@H]1[C@@H](O)[C@H](N(C=C2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO
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Purity & Documentation
References
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7-Deazaguanosine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Deazaguanosine62160-23-0Nucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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