2. JAK/STAT Signaling Stem Cell/Wnt Apoptosis
  3. STAT Apoptosis
  4. 7-epi-Isogarcinol

7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration.

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7-epi-Isogarcinol Chemical Structure

7-epi-Isogarcinol Chemical Structure

CAS No. : 1141378-40-6

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Based on 1 publication(s) in Google Scholar

7-epi-Isogarcinol Related Antibodies

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STAT3 STAT5 STAT6 STAT1

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Description

7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration[1].

IC50 & Target[1]

STAT3

 

Molecular Weight

602.80

Formula

C38H50O6
CAS No.
SMILES

O=C1[C@@]23C(OC(C)([C@H](C3)C/C=C(C)\C)C)=C(C([C@@]1(C(C)([C@H](C2)C/C=C(C)\C)C)C/C=C(C)\C)=O)C(C4=CC(O)=C(C=C4)O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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7-epi-Isogarcinol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-epi-Isogarcinol1141378-40-6STATApoptosispolycyclic polyprenylated acylphloroglucinolPPAPInhibitorinhibitorinhibit

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