1. Signaling Pathways
  2. JAK/STAT Signaling
    Stem Cell/Wnt
  3. STAT
  4. STAT Inhibitors

STAT Inhibitors

STAT3

STAT5

STAT6

STAT1

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

STAT Degraders, Inhibitors & Activators
Product Name STAT3 STAT5 STAT6 STAT1 Purity
Stattic
STAT3
      99.58%
AG490
Stat-3
      99.86%
Cilengitide
STAT3 ([3])
      99.80%
Homoharringtonine
STAT3
      99.96%
Ac-GpYLPQTV-NH2 acetate
STAT3, IC50: 0.33 μM
      99.38%
AS1517499    
STAT6, IC50: 21 nM
  99.17%
Artesunate
Stat-3
      99.84%
Niclosamide
STAT3, IC50: 0.25 μM (in HeLa cells)
      99.91%
C188-9
STAT3, Kd: 4.7 nM
      99.90%
GYY4137
Stat-3
      98.08%
NSC 74859
STAT3, IC50: 86 μM
      98.35%
Butyzamide
STAT3
STAT5
    99.62%
TPCA-1
STAT3
      99.66%
Colivelin
STAT3
      99.27%
WP1066
STAT3
      99.77%
Astaxanthin
STAT3
      ≥98.0%
Scutellarin
STAT3
      99.04%
Napabucasin
STAT3
      99.94%
Cryptotanshinone
STAT3, IC50: 4.6 μM
      98.80%
STAT5-IN-1  
STAT5β, IC50: 47 μM
    98.35%
Pimozide
STAT3
STAT5
    99.91%
Colivelin TFA
STAT3
      99.52%
SD-36
STAT3, Kd: 50 nM
      99.73%
Diosgenin
STAT3
      99.35%
Saikosaponin D
STAT3
      98.76%
AC-4-130  
STAT5
    99.93%
Cucurbitacin I
STAT3
      99.44%
Morusin
STAT3
      99.94%
AS2863619  
STAT5
    99.94%
SH-4-54
STAT3, Kd: 300 nM
STAT5, Kd: 464 nM
    99.45%
BP-1-102
STAT3, IC50: 6.8 μM
      99.52%
SI-109
STAT3, Ki: 9 nM
      99.91%
Nifuroxazide
STAT3
      99.90%
Alantolactone
STAT3
      99.94%
SC-43
p-STAT3
      99.02%
STAT3-IN-1
Stat-3, IC50: 1.82 μM (in HT29 cells)
Stat-3, IC50: 2.14 μM (in MDA-MB 231 cells)
     
YM-341619    
STAT6, IC50: 0.70 nM
  99.06%
AK-2292  
STAT5, DC50: 0.10 μM
    99.73%
AS1810722    
STAT6, IC50: 1.9 nM
  98.14%
Erasin
STAT3, IC50: 9.7 μM
   
STAT1, IC50: 24 μM
NSC-370284
STAT3
STAT5
   
1-Stearoyl-sn-glycero-3-phosphocholine
p-STAT3
      99.53%
Atractylenolide II
p-STAT3
      99.94%
Peramivir
STAT3
      99.32%
Brevilin A
STAT3, IC50: 10.6 μM
      99.81%
Stafia-1  
STAT5a, Ki: 10.9 μM
STAT5a, IC50: 22.2 μM
    99.37%
Broussonin E
STAT3
      98.18%
HJC0152
STAT3
      99.76%
Flubendazole
STAT3
      99.33%
STAT3-IN-3
STAT3
      98.40%
HO-3867
STAT3
      99.67%
Perindopril erbumine
STAT3
      99.98%
Picroside I    
STAT6
  99.55%
Garcinone D
p-STAT3
      99.88%
BD750  
STAT5
    99.10%
Stafib-1  
STAT5b, IC50: 154 nM
    ≥98.0%
LLL12
p-STAT3
      99.45%
GMB-475  
STAT5
    98.98%
STX-0119
STAT3, IC50: 74 μM (STAT3 transcription)
      99.21%
Cenisertib  
STAT5
    99.86%
Ginkgolic acid C17:1
STAT3
      99.90%
IST5-002  
STAT5a, IC50: 1.5 μM
STAT5b, IC50: 3.5 μM
    99.36%
inS3-54A18
STAT3
      99.53%
STAT3-IN-25
STAT3
      99.36%
Triacetylresveratrol
STAT3
      99.58%
OSM-SMI-10B
p-STAT3
      99.28%
Mogrol
STAT3
      99.76%
Corylifol A
STAT3, IC50: 0.81 μM
      99.90%
STAT3-IN-12
STAT3
      99.92%
STAT5-IN-2  
STAT5, EC50: 9 μM (in K562 cells)
STAT5, EC50: 5 μM (in KU812 cells )
    99.08%
Ochromycinone
STAT3
      98.29%
Garcinone C
Stat-3
      99.66%
Reticuline
STAT3
      98.91%
Golotimod hydrochloride
STAT3
      99.79%
Perindopril
STAT3
      98.01%
Protosappanin A
STAT3
      99.98%
HODHBt  
STAT5
    99.93%
Tetramethylcurcumin
STAT3
      99.91%
Arnicolide D
STAT3
      99.69%
AS2863619 free base  
STAT5
    99.87%
LL-K8-22      
STAT1
99.76%
Balsalazide
STAT3
      99.34%
STAT3-IN-15
STAT3
      98.99%
YMU1
STAT3
      99.19%
KT-333
STAT3
     
HJC0416 hydrochloride
STAT3
      98.68%
Golotimod
STAT3
      98.04%
PROTAC FLT-3 degrader 1  
STAT5
    99.74%
STAT3-IN-17
STAT3
      ≥98.0%
SC99
STAT3
      98.96%
ASP3026
STAT3
      99.88%
OK2
p-STAT3
     
Equisetin
STAT3
      99.40%
UC-514321
STAT3
STAT5
    ≥98.0%
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
p-STAT3
      98.02%
Balsalazide sodium hydrate
STAT3
      99.61%
WB436B
STAT3
      99.93%
SH5-07
STAT3, IC50: 3.9 μM
      ≥98.0%
MNK8
STAT3
      99.76%
ENMD-1198
STAT3
      98.87%
SB02024      
STAT1
99.7%
Syk-IN-6
STAT3
STAT5
   
SD-1029
STAT3
     
Vanicoside B
STAT3
      99.82%
APTSTAT3-9R
STAT3
      99.55%
Iminostilbene
STAT3
      99.34%
Pimozide-d4
STAT3
STAT5
    ≥98.0%
Galiellalactone
STAT3, IC50: 250-500 nM
     
Eflepedocokin alfa
STAT3
      ≥99.0%
Biflorin      
STAT1
99.54%
Stafia-1-dipivaloyloxymethyl ester  
STAT5a
    98.31%
Eupalinolide K
STAT3
      99.20%
Niclosamide monohydrate
STAT3, IC50: 0.25 μM (in HeLa cells)
     
SD-1008
STAT3
      99.10%
STAT3-IN-8
STAT3
     
KT-333 diammonium
STAT3
     
YSY01A
Stat-3
     
c-Met-IN-24
STAT3, IC50: 4.7 μM
     
STAT3-IN-37
STAT3
     
STAT3 HiBiT degrader 1
STAT3
     
STAT3-IN-38
STAT3, Kd: 45.33 μM
     
STAT3-IN-29
STAT3
     
VEGFR-2/STAT-3-IN-1
STAT3, IC50: 5.63 nM
     
8α-Tigloyloxyhirsutinolide 13-O-acetate
STAT3
     
STAT1/3-IN-1
STAT3
   
STAT1
KT-333 ammonium
STAT3
     
WR-S-462
STAT3, Kd: 58 nM
     
JAK1/STAT3-IN-1
STAT3
     
FLT3-IN-28  
STAT5
   
SD-436
STAT3, IC50: 19 nM
STAT5, IC50: >10 μM
STAT6, IC50: >10 μM
STAT1, IC50: 270 nM
STAT3/AKT-IN-1
Stat-3
     
ROCK2-IN-7
Stat-3
     
Anti-inflammatory agent 92
STAT3
     
STAT3-IN-41
STAT3
     
Golotimod TFA
STAT3
     
HJC0416
STAT3
     
HJC0123
STAT3
     
HAT-SIL-TG-1&AT
STAT3
STAT5
   
7-epi-Isogarcinol
STAT3
     
Cernuumolide J
Stat-3
     
Atractylenolide II (Standard)
p-STAT3
     
Antitumor agent-73
STAT3
     
STAT3-IN-5
p-STAT3, EC50: 170 nM
     
K882
Stat-3
     
STAT3-IN-32
STAT3
     
WB518
STAT3
p-STAT3
     
Hsp110-STAT3 interaction-IN-2
STAT3
     
Ac-GpYLPQTV-NH2
STAT3, IC50: 0.33 μM
     
STAT3-IN-9
STAT3
     
PROTAC STAT3 degrader-2
STAT3, ID50: 3.54 μM
     
Ascochlorin
STAT3
     
Tyk2-IN-22-d3  
STAT5
   
1-Stearoyl-sn-glycero-3-phosphocholine-d35
p-STAT3
     
NW16
STAT3, Kd: 11.0 μM
     
15(R)-Lipoxin A4    
STAT6
 
Furowanin A
STAT3
     
Antitumor agent-195
STAT3, IC50: 0.52 μM
     
STAT3-IN-10
STAT3, IC50: 5.18 μM
     
Balsalazide disodium
STAT3
     
GYY4137 (GMP)
Stat-3
     
CHMFL-48  
STAT5
   
DETD-35
Stat-3
     
STAT3-IN-39
STAT3
     
TM-233
Stat-3
     
BP-1-108  
STAT5, Ki: 8.3 μM
   
PMMB-187
Stat-3, IC50: 1.81 μM