2. Natural Products
  3. Plants Phenylpropanoids
  4. Rutaceae Coumarins
  5. Atalantia buxifolia (Poir.) Oliv.
  6. 7-O-Geranylscopoletin

7-O-Geranylscopoletin  (Synonyms: 7-Geranyloxy-6-methoxycoumarin)

Cat. No.: HY-N2746 Purity: ≥97.0%
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7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia.

For research use only. We do not sell to patients.

7-O-Geranylscopoletin Chemical Structure

7-O-Geranylscopoletin Chemical Structure

CAS No. : 28587-43-1

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Based on 1 publication(s) in Google Scholar

7-O-Geranylscopoletin Related Antibodies

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Description

7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia[1].

Cellular Effect
Cell Line Type Value Description References
T47D IC50
17.5 μM
Compound: 7
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to 1% O2-challenge measured after 16 hrs by luciferase reporter assay
[PMID: 23434131]
T47D IC50
24.2 μM
Compound: 7
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
[PMID: 23434131]
Molecular Weight

328.40

Formula

C20H24O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C=CC2=CC(OC)=C(OC/C=C(C)/CC/C=C(C)/C)C=C2O1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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7-O-Geranylscopoletin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-O-Geranylscopoletin28587-43-17-Geranyloxy-6-methoxycoumarinOthersInhibitorinhibitorinhibit

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