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  6. 7-Xylosyl-10-Deacetyltaxol B

7-Xylosyl-10-Deacetyltaxol B  (Synonyms: 7-xylosyl-10-Deacetylpaclitaxel B)

Cat. No.: HY-N7776
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7-Xylosyl-10-Deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol B has anti-tumor activity and inhibits the growth of S180 sarcoma.

For research use only. We do not sell to patients.

7-Xylosyl-10-Deacetyltaxol B Chemical Structure

7-Xylosyl-10-Deacetyltaxol B Chemical Structure

CAS No. : 90332-64-2

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Based on 1 publication(s) in Google Scholar

7-Xylosyl-10-Deacetyltaxol B Related Antibodies

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Description

7-Xylosyl-10-Deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol B has anti-tumor activity and inhibits the growth of S180 sarcoma[1].

Cellular Effect
Cell Line Type Value Description References
A2780 IC50
3.5 μM
Compound: 10
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
1.9 μM
Compound: 10
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
3.1 μM
Compound: 10
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HCT-8 IC50
> 25 μM
Compound: 10
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HepG2 IC50
3.9 μM
Compound: 10
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
MCF7 IC50
0.14 μM
Compound: 10
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
NIH3T3 IC50
> 25 μM
Compound: 10
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
SW480 IC50
20 μM
Compound: 10
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
Molecular Weight

921.98

Formula

C48H59NO17
CAS No.
SMILES

CC(O[C@]([C@@]1([H])C[C@@H]2O[C@@](OC[C@H]3O)([H])[C@@H]([C@H]3O)O)(CO1)[C@]([C@@H]([C@@](C4(C)C)(C[C@@H]5OC([C@H](O)[C@H](C6=CC=CC=C6)NC(/C(C)=C/C)=O)=O)O)OC(C7=CC=CC=C7)=O)([H])[C@@]2(C([C@@H](C4=C5C)O)=O)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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7-Xylosyl-10-Deacetyltaxol B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Xylosyl-10-Deacetyltaxol B90332-64-27-xylosyl-10-Deacetylpaclitaxel BOthersT. cuspidatepaclitaxel derivativeanti-tumorS180 sarcomaInhibitorinhibitorinhibit

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