2. Cell Cycle/DNA Damage
  3. PERK
  4. 7DG

7DG  (Synonyms: 7-Desacetoxy-6,7-dehydrogedunin)

Cat. No.: HY-124857
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7DG (7-Desacetoxy-6,7-dehydrogedunin) is a protein kinase R (PKR) inhibitor. 7DG protects macrophages from lethal toxin-induced pyroptosis.

For research use only. We do not sell to patients.

7DG Chemical Structure

7DG Chemical Structure

CAS No. : 26927-01-5

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7DG Related Antibodies

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Description

7DG (7-Desacetoxy-6,7-dehydrogedunin) is a protein kinase R (PKR) inhibitor. 7DG protects macrophages from lethal toxin-induced pyroptosis[1].

IC50 & Target

protein kinase R (PKR)[1]
Molecular Weight

422.51

Formula

C26H30O5
CAS No.
SMILES

O=C1O[C@@H](C2=COC=C2)[C@]3(C)CC[C@@]4([H])[C@](C=C[C@@]5([H])C(C)(C)C(C=C[C@@]54C)=O)(C)[C@@]36[C@@H]1O6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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7DG Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7DG26927-01-57-Desacetoxy-6,7-dehydrogeduninPERKProtein kinase R-like endoplasmic reticulum kinasePKR-like endoplasmic reticulum kinasePKRpyroptosisInhibitorinhibitorinhibit

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