7α,24(S)-Dihydroxycholesterol  (Synonyms: (3β,7α,24S)-Cholest-5-ene-3,7,24-triol)

7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) serves as a ligand for liver X receptor (LXR), binding specifically to the ligand binding domains of both LXRα and LXRβ. This compound is synthetically produced from E-α,β-enone, utilizing Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde as starting materials, followed by a series of transformations to yield 7α,24(S)-dihydroxycholesterol.

418.65

C₂₇H₄₆O₃

245523-67-5

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@H](O)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@H]3O)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Effect of pressure on the bilayer phase transitions of asymmetric lipids with an unsaturated acyl chain in sn-1 positionJournal of physical activity & health

  [2]. Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine

  [3]. Inflammatory Bowel DiseaseIntegrative Medicine

  [4]. Barotropic and thermotropic bilayer phase behavior of positional isomers of unsaturated mixed-chain phosphatidylcholines