2. Natural Products
  3. Plants Terpenoids
  4. Paeoniaceae Other Monoterpenes
  5. Paeonia suffruticosa Andr.
  6. 8-Debenzoylpaeoniflorin

8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity.

For research use only. We do not sell to patients.

8-Debenzoylpaeoniflorin Chemical Structure

8-Debenzoylpaeoniflorin Chemical Structure

CAS No. : 23532-11-8

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8-Debenzoylpaeoniflorin Related Antibodies

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Description

8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
74.22 μM
Compound: 17
Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess reaction
Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess reaction
[PMID: 23067550]
In Vivo

8-Debenzoylpaeoniflorin (1-10 mg/kg; i.v.; single dose) has antihyperglycemic activity and decreases plasma glucose levels in STZ-diabetic rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar STZ-diabetic rats (210-250g)[1]
Dosage: 1, 5, and 10 mg/kg
Administration: Intravenous injection, single dose
Result: Decreased plasma glucose levels in a time- and dose-dependent manner in STZ-diabetic rats.
Molecular Weight

376.36

Formula

C16H24O10
CAS No.
SMILES

OC[C@@]12[C@]3([C@]4(O[C@@H]1O[C@@]([C@@H]2C3)(C4)O)C)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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8-Debenzoylpaeoniflorin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Debenzoylpaeoniflorin23532-11-8Othersmonoterpene glycosidePaeonia lactiflora PallrootantihyperglycemicInhibitorinhibitorinhibit

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