8-Pcpt-cGMP sodium

Name: 8-Pcpt-cGMP sodium
Brand: MedChemExpress
SKU: HY-137016A
Rating: 4.5 (1 reviews)

Cat. No.: HY-137016A Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

8-Pcpt-cGMP sodium is the sodium salt form of 8-Pcpt-cGMP (HY-137016). 8-Pcpt-cGMP sodium is an agonist for cyclic nucleotide-gated (CNG) channel with an EC₅₀ of 0.5 μM. 8-Pcpt-cGMP sodium exhibits good membrane permeability. 8-Pcpt-cGMP sodium can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction.

For research use only. We do not sell to patients.

8-Pcpt-cGMP sodium Chemical Structure

CAS No. : 51239-26-0

Size	Price	Stock	Quantity
5 mg	USD 148	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 8-Pcpt-cGMP sodium:

8-Pcpt-cGMP Get quote

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References
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Description

IC₅₀ & Target

EC₅₀: 0.5 μM (CNG Channel)

Molecular Weight

509.79

Formula

C₁₆H₁₄ClN₅NaO₇PS

CAS No.

51239-26-0

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@](O[C@@](CO2)([H])[C@@]1([H])O[P]2(O[Na])=O)([H])N3C(NC(N)=NC4=O)=C4N=C3SC(C=C5)=CC=C5Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (49.04 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9616 mL	9.8080 mL	19.6159 mL
5 mM	0.3923 mL	1.9616 mL	3.9232 mL
10 mM	0.1962 mL	0.9808 mL	1.9616 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (279 KB) SDS (252 KB)

COA (262 KB)

Handling Instructions (2659 KB)

References

[1]. Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9616 mL	9.8080 mL	19.6159 mL	49.0398 mL
	5 mM	0.3923 mL	1.9616 mL	3.9232 mL	9.8080 mL
	10 mM	0.1962 mL	0.9808 mL	1.9616 mL	4.9040 mL
	15 mM	0.1308 mL	0.6539 mL	1.3077 mL	3.2693 mL
	20 mM	0.0981 mL	0.4904 mL	0.9808 mL	2.4520 mL
	25 mM	0.0785 mL	0.3923 mL	0.7846 mL	1.9616 mL
	30 mM	0.0654 mL	0.3269 mL	0.6539 mL	1.6347 mL
	40 mM	0.0490 mL	0.2452 mL	0.4904 mL	1.2260 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.