2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. AGN 210676

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

For research use only. We do not sell to patients.

AGN 210676 Chemical Structure

AGN 210676 Chemical Structure

CAS No. : 910562-15-1

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AGN 210676 Related Antibodies

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Description

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

IC50 & Target[1]

EP2

5 nM (EC50)

hEP3

153 nM (EC50)

hDP receptor

7749 nM (EC50)

In Vitro

AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AGN 210676 Related Antibodies
Molecular Weight

431.55

Formula

C23H29NO5S
CAS No.
SMILES

O=C(C1=CC=C(COC[C@@H](CC2)N(C3=CC=C([C@@H](O)CCCCC)C=C3)C2=O)S1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AGN 210676 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AGN 210676910562-15-1SimenepagAGN210676AGN-210676Prostaglandin ReceptorInhibitorinhibitorinhibit

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HY-14898
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