2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. BCR-ABL-IN-1

BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

For research use only. We do not sell to patients.

BCR-ABL-IN-1 Chemical Structure

BCR-ABL-IN-1 Chemical Structure

CAS No. : 188260-50-6

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BCR-ABL-IN-1 Related Antibodies

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Description

BCR-ABL-IN-1 is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

IC50 & Target

pIC50: 6.46 (BCR-ABL)[1]
In Vitro

BCR-ABL-IN-1 (Compound 21) is an inhibitor of BCR-ABL tyrosine kinase, with a pIC50 of 6.46, and may be used in the research of chronic myelogenous leukemia.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BCR-ABL-IN-1 Related Antibodies
Molecular Weight

459.44

Formula

C23H21F4N5O
CAS No.
SMILES

NCCCN1C=CC2=C1C=CC=C2C3=NC(NC4=CC=CC(OC(F)(F)C(F)F)=C4)=NC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BCR-ABL-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BCR-ABL-IN-1188260-50-6Bcr-AblInhibitorinhibitorinhibit

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