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  5. Ceanothic acid

Ceanothic acid  (Synonyms: Emmolic acid)

Cat. No.: HY-N3558 Purity: ≥98.0%
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Ceanothic acid (Emmolic acid) is a ring-A homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively.

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Ceanothic acid Chemical Structure

Ceanothic acid Chemical Structure

CAS No. : 21302-79-4

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Based on 1 publication(s) in Google Scholar

Ceanothic acid Related Antibodies

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Description

Ceanothic acid (Emmolic acid) is a ring-A homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively[1].

Cellular Effect
Cell Line Type Value Description References
C3H 10T1/2 IC50
> 200 μM
Compound: 5
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
DU-145 IC50
> 200 μM
Compound: 5
Cytotoxicity against human DU145 cells after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against human DU145 cells after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
HaCaT IC50
> 200 μM
Compound: 5
Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay
Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assay
[PMID: 18842418]
HepG2 IC50
> 10 μM
Compound: 19
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
[PMID: 27617953]
PANC-1 IC50
195 μM
Compound: 5
Cytotoxicity against human PANC1 after 24 hrs by fluorometric microculture cytotoxicity assay
Cytotoxicity against human PANC1 after 24 hrs by fluorometric microculture cytotoxicity assay
[PMID: 18842418]
Molecular Weight

486.68

Formula

C30H46O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@]([C@]4([C@]([C@]5([H])[C@](C(O)=O)(CC[C@H]5C(C)=C)CC4)([H])CC3)C)(CC[C@@]1([H])C(C)(C)[C@@H](O)[C@@H]2C(O)=O)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

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COA (263 KB)

Handling Instructions (2659 KB)
References
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Ceanothic acid Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ceanothic acid21302-79-4Emmolic acidOthersInhibitorinhibitorinhibit

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