2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. Enalaprilat-d5 sodium

Enalaprilat-d5 sodium  (Synonyms: MK-422-d5 sodium)

Cat. No.: HY-B0231BS Purity: ≥98.0%
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Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.

For research use only. We do not sell to patients.

Enalaprilat-d<sub>5</sub> sodium Chemical Structure

Enalaprilat-d5 sodium Chemical Structure

CAS No. : 1356922-29-6

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1 mg USD 276 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.

Molecular Weight

397.39

Formula

C18H17D5N2Na2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](C(N1CCC[C@H]1C(O[Na])=O)=O)N[C@H](C(O[Na])=O)CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (251.64 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5164 mL 12.5821 mL 25.1642 mL
5 mM 0.5033 mL 2.5164 mL 5.0328 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (252 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5164 mL 12.5821 mL 25.1642 mL 62.9105 mL
5 mM 0.5033 mL 2.5164 mL 5.0328 mL 12.5821 mL
10 mM 0.2516 mL 1.2582 mL 2.5164 mL 6.2910 mL
15 mM 0.1678 mL 0.8388 mL 1.6776 mL 4.1940 mL
20 mM 0.1258 mL 0.6291 mL 1.2582 mL 3.1455 mL
25 mM 0.1007 mL 0.5033 mL 1.0066 mL 2.5164 mL
30 mM 0.0839 mL 0.4194 mL 0.8388 mL 2.0970 mL
40 mM 0.0629 mL 0.3146 mL 0.6291 mL 1.5728 mL
50 mM 0.0503 mL 0.2516 mL 0.5033 mL 1.2582 mL
60 mM 0.0419 mL 0.2097 mL 0.4194 mL 1.0485 mL
80 mM 0.0315 mL 0.1573 mL 0.3146 mL 0.7864 mL
100 mM 0.0252 mL 0.1258 mL 0.2516 mL 0.6291 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Enalaprilat-d5 sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enalaprilat-d51356922-29-6MK-422-d5Angiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

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