2. Metabolic Enzyme/Protease
  3. Acyltransferase
  4. FR-190809

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.

For research use only. We do not sell to patients.

FR-190809 Chemical Structure

FR-190809 Chemical Structure

CAS No. : 215589-63-2

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FR-190809 Related Antibodies

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ACAT1 ACAT2 MGAT2 ACAT

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Description

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM[1].

IC50 & Target

IC50: (ACAT)[1]
In Vitro

FR-190809 inhibits foam cell formation with an IC50 of 215 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FR-190809 Related Antibodies
Molecular Weight

603.73

Formula

C29H34FN3O6S2
CAS No.
SMILES

O=C(NC1=C(S(=O)(C)=O)C=C(C)N=C1S(=O)(C)=O)N(C2CCCCCC2)CC3=CC=C(OC4=CC=C(F)C=C4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FR-190809 Related Classifications

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  • Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FR-190809215589-63-2FR190809FR 190809AcyltransferaseDiacylglycerol acyltransferaseDiglyceride acyltransferaseacyl-CoA:cholesterol acyltransferasemono- acylglycerol acyltransferaseInhibitorinhibitorinhibit

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HY-122078
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