1. Metabolic Enzyme/Protease
  2. Farnesyl Transferase
  3. FTI 276

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (FTI 276 TFA) that retains the same biological activity.

For research use only. We do not sell to patients.

FTI 276 Chemical Structure

FTI 276 Chemical Structure

CAS No. : 170006-72-1

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Description

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 and 0.5 nM for Plasmodium falciparum and human.

IC50 & Target

IC50: 0.9 and 0.5 nM for Plasmodium falciparum and human[1].

Molecular Weight

433.59

Formula

C21H27N3O3S2

CAS No.
SMILES

O=C(O)[C@@H](NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=CC=CC=C2)=O)CCSC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
FTI 276
Cat. No.:
HY-15873
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