Flagelin 22 (Synonyms: Flagellin 22)

Cat. No.: HY-P1568: FAQs
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Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.

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Flagelin 22 Chemical Structure

CAS No. : 304642-91-9

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Other In-stock Forms of Flagelin 22:

Flagelin 22 TFA

Other Forms of Flagelin 22:

Flagelin 22 TFA In-stock

3 Publications Citing Use of MCE Flagelin 22

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Description	Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae^[1]^[2]^[3].
In Vitro	Flagelin 22 (100 nM, 1 or 24 h) activates a gene that triggers immunity (PTI) and leads to reduced expression of growth-promoting hormone brassinolide (BR) biosynthesis in plants^[2]. Flagelin 22 (10 μM, 4 h) regulates the release of ethylene reactive factor substrate in Arabidopsis MAP kinase 6 by ethylene signaling^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Flagelin 22 Related Antibodies
Molecular Weight	2272.48
Formula	C₉₃H₁₆₂N₃₂O₃₄
CAS No.	304642-91-9
Sequence	Gln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala
Sequence Shortening	QRLSTGSRINSAKDDAAGLQIA
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (263 KB) Handling Instructions (2659 KB)
References	[1]. Bojun Lu, et al. Defense responses in female gametophytes of Saccharina japonica (Phaeophyta) induced by flg22-derived peptides. Journal of Applied Phycology (2016), 28(3), 1793-1801. [2]. Jiménez-Góngora T, et al. Flg22-Triggered Immunity Negatively Regulates Key BR Biosynthetic Genes. Front Plant Sci. 2015 Nov 9;6:981. [Content Brief] [3]. Bethke G, et al. Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling. Proc Natl Acad Sci U S A. 2009 May 12;106(19):8067-72. [Content Brief]

Cell Assay
^[1]

One milliliter of the female gametophytes is added to 100 mL sterilized seawater containing 1 μM of Flagelin 22, flg15, flg14, and flg22D43A, respectively. Controls are sterilized seawater and 0.1% BSA in sterilized seawater. Gametophytes are grown at 10°C with a 24-h photoperiod at 50 μmol photons m^-2 s^-1. Sterilized seawater medium is provided with 0.2 mM KNO₃, 0.02mM KH₂PO₄, and 1 μM of the four respective peptides and refreshed every week. The gametophytes are briefly blotted dry, and the fresh weight is measured after 40 days^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. Bojun Lu, et al. Defense responses in female gametophytes of Saccharina japonica (Phaeophyta) induced by flg22-derived peptides. Journal of Applied Phycology (2016), 28(3), 1793-1801.

[2]. Jiménez-Góngora T, et al. Flg22-Triggered Immunity Negatively Regulates Key BR Biosynthetic Genes. Front Plant Sci. 2015 Nov 9;6:981. [Content Brief]

[3]. Bethke G, et al. Flg22 regulates the release of an ethylene response factor substrate from MAP kinase 6 in Arabidopsis thaliana via ethylene signaling. Proc Natl Acad Sci U S A. 2009 May 12;106(19):8067-72. [Content Brief]

Flagelin 22 Related Classifications

Infection

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flagelin 22304642-91-9Flagellin 22Flagelin22Flagelin-22Flagellin22Flagellin-22BacterialFlg22PTIBRMAPK6Plant InducersInhibitorinhibitorinhibit

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