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GLUFOSFAMIDE  (Synonyms: D 19575; Glucosylifosfamide mustard)

Cat. No.: HY-16232 Purity: ≥98.0%
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Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.

For research use only. We do not sell to patients.

GLUFOSFAMIDE Chemical Structure

GLUFOSFAMIDE Chemical Structure

CAS No. : 132682-98-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 352 In-stock
Solution
10 mM * 1 mL in Water USD 352 In-stock
Solid
5 mg USD 320 In-stock
10 mg USD 510 In-stock
25 mg USD 1050 In-stock
50 mg USD 1680 In-stock
100 mg USD 2650 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

GLUFOSFAMIDE Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.

Clinical Trial
Molecular Weight

383.16

Formula

C10H21Cl2N2O7P
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O[C@@H]1[C@@H](O)[C@H](OP(NCCCl)(NCCCl)=O)O[C@H](CO)[C@H]1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (326.23 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6099 mL 13.0493 mL 26.0986 mL
5 mM 0.5220 mL 2.6099 mL 5.2197 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (130.49 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6099 mL 13.0493 mL 26.0986 mL 65.2464 mL
5 mM 0.5220 mL 2.6099 mL 5.2197 mL 13.0493 mL
10 mM 0.2610 mL 1.3049 mL 2.6099 mL 6.5246 mL
15 mM 0.1740 mL 0.8700 mL 1.7399 mL 4.3498 mL
20 mM 0.1305 mL 0.6525 mL 1.3049 mL 3.2623 mL
25 mM 0.1044 mL 0.5220 mL 1.0439 mL 2.6099 mL
30 mM 0.0870 mL 0.4350 mL 0.8700 mL 2.1749 mL
40 mM 0.0652 mL 0.3262 mL 0.6525 mL 1.6312 mL
50 mM 0.0522 mL 0.2610 mL 0.5220 mL 1.3049 mL
60 mM 0.0435 mL 0.2175 mL 0.4350 mL 1.0874 mL
80 mM 0.0326 mL 0.1631 mL 0.3262 mL 0.8156 mL
100 mM 0.0261 mL 0.1305 mL 0.2610 mL 0.6525 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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GLUFOSFAMIDE Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLUFOSFAMIDE132682-98-5D 19575 Glucosylifosfamide mustardD19575D-19575OthersInhibitorinhibitorinhibit

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