HAEGTFTSDVS 

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity^[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1150.15

C₄₈H₇₁N₁₃O₂₀

864915-61-7

Solid

White to off-white

His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser

HAEGTFTSDVS

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. US20120264685

  [2]. US9738697