1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel Potassium Channel Sodium Channel
  3. Myomodulin

Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.

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Myomodulin Chemical Structure

Myomodulin Chemical Structure

CAS No. : 110570-93-9

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Description

Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.

In Vitro

Myomodulin decreases period and increases spike frequency in oscillator heart interneurons. Myomodulin enhances the hyperpolarization-activated cation current and inhibits the electrogenic Na/K pump[1]. A myomodulin peptide has been suggested to mediate the response of the giant glial cells to stimulation of the Leydig interneuron in the central nervous system of the leech Hirudo medicinalis. The peptide evokes a membrane outward current (EC50 approximately 2 μM), which neither desensitizes nor shows any sign of run-down, and elicits a K+ conductance increase of the glial cell membrane[2]. Myomodulin modulate ion channels in a wide variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. Myomodulin differentially modulates the potassium currents and reduces the amplitude of the Ca2+ current by 20%[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

846.12

Formula

C36H67N11O8S2

CAS No.
Sequence

Pro-Met-Ser-Met-Leu-Arg-Leu-NH2

Sequence Shortening

PMSMLRL-NH2

Structure Classification
Initial Source

molluscs, insects, and gastropods

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Myomodulin
Cat. No.:
HY-P0268
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