2. Metabolic Enzyme/Protease Others
  3. Drug Metabolite Isotope-Labeled Compounds
  4. N-Demethyl Ivabradine-d6 hydrochloride

N-Demethyl Ivabradine-d6 hydrochloride 

Cat. No.: HY-12778S Purity: ≥98.0%
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N-Demethyl Ivabradine-d6 (hydrochloride) is the deuterium labeled N-Demethyl Ivabradine, which is a metabolite of Ivabradine.

For research use only. We do not sell to patients.

N-Demethyl Ivabradine-d<sub>6</sub> hydrochloride Chemical Structure

N-Demethyl Ivabradine-d6 hydrochloride Chemical Structure

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1 mg USD 600 In-stock
5 mg USD 1600 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Demethyl Ivabradine-d6 hydrochloride:

N-Demethyl Ivabradine-d6 hydrochloride Related Antibodies

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Description

N-Demethyl Ivabradine-d6 (hydrochloride) is the deuterium labeled N-Demethyl Ivabradine, which is a metabolite of Ivabradine.

Molecular Weight

497.06

Formula

C26H29D6ClN2O5
Unlabeled CAS

1246638-08-3
Appearance

Solid

Color

White to off-white

SMILES

O=C1N(CCCNC[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)CCC4=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C4C1.Cl
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (100.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0118 mL 10.0591 mL 20.1183 mL
5 mM 0.4024 mL 2.0118 mL 4.0237 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0118 mL 10.0591 mL 20.1183 mL 50.2957 mL
5 mM 0.4024 mL 2.0118 mL 4.0237 mL 10.0591 mL
10 mM 0.2012 mL 1.0059 mL 2.0118 mL 5.0296 mL
15 mM 0.1341 mL 0.6706 mL 1.3412 mL 3.3530 mL
20 mM 0.1006 mL 0.5030 mL 1.0059 mL 2.5148 mL
25 mM 0.0805 mL 0.4024 mL 0.8047 mL 2.0118 mL
30 mM 0.0671 mL 0.3353 mL 0.6706 mL 1.6765 mL
40 mM 0.0503 mL 0.2515 mL 0.5030 mL 1.2574 mL
50 mM 0.0402 mL 0.2012 mL 0.4024 mL 1.0059 mL
60 mM 0.0335 mL 0.1677 mL 0.3353 mL 0.8383 mL
80 mM 0.0251 mL 0.1257 mL 0.2515 mL 0.6287 mL
100 mM 0.0201 mL 0.1006 mL 0.2012 mL 0.5030 mL
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N-Demethyl Ivabradine-d6 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Demethyl Ivabradine-d6Drug MetaboliteIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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