2. Natural Products
  3. Plants
  4. Hippocastanaceae
  5. Aesculus chinensis Bunge

Aesculus chinensis Bunge

Aesculus chinensis Bunge (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0556
    Isoescin IA 219944-39-5 98.90%
    Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity.
    Isoescin IA
  • HY-N13115A
    Protoescigenin 21-tiglate 7047-43-0
    Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively.
    Protoescigenin 21-tiglate
  • HY-N13115
    21-Angeloyl-protoaescigenin 35931-54-5
    21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively.
    21-Angeloyl-protoaescigenin
  • HY-N13082
    Deacetylescin Ia 254896-53-2
    Deacetylescin Ia (compound 12) is a deacetylated compound with anti-hyperglycemic effects that can be extracted from the debittered Aesculus and deacetylated at the C-22 position. Deacetylescin Ia (100 mg/kg) can inhibit blood glucose elevation in mouse glucose tolerance tests.
    Deacetylescin Ia
  • HY-N0556R
    Isoescin IA (Standard) 219944-39-5
    Isoescin IA (Standard) is the analytical standard of Isoescin IA. This product is intended for research and analytical applications. Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity.
    Isoescin IA (Standard)