2. Natural Products
  3. Plants
  4. Combretaceae
  5. Buchenavia macrophylla Spruce ex Eichler

Buchenavia macrophylla Spruce ex Eichler

Buchenavia macrophylla Spruce ex Eichler (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12625
    (R)-(+)-O-Demethylbuchenavianine 1364123-68-1 98.67%
    (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively.
    (R)-(+)-O-Demethylbuchenavianine
  • HY-N12625A
    (S)-(-)-O-Demethylbuchenavianine 91147-18-1
    (S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1) is a flavonoidal alkaloids. (S)-(-)-O-Demethylbuchenavianine is a potent CDK inhibitor, with IC50 values of 0.03 and 0.05 μM for CDK1 and CDK5, respectively.
    (S)-(-)-O-Demethylbuchenavianine