2. Natural Products
  3. Plants
  4. Menispermaceae
  5. Stephania epigaea Lo

Stephania epigaea Lo

Stephania epigaea Lo (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6969
    Dicentrine 517-66-8 99.38%
    Dicentrine is a natural product isolated from the plant Stephania epigaea Lo with antihypertensive effect. Dicentrine is an α1-adrenoceptor antagonist which has effective against human hyperplastic prostates.
    Dicentrine
  • HY-N2569
    (-)-Curine 436-05-5
    (-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production.
    (-)-Curine
  • HY-N2034
    Dehydrodicentrine 19843-03-9
    Dehydrodicentrine is an alkaloid inhibitor of acetylcholinesterase (AChE) (IC50=2.98 μM). Dehydrodicentrine.
    Dehydrodicentrine
  • HY-N3185
    N-Methylcalycinine 86537-66-8
    N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on.
    N-Methylcalycinine
  • HY-N6969A
    Dicentrine hydrochloride 5742-03-0
    Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-α-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-α-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-α-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-κB and AP-1.
    Dicentrine hydrochloride