2. Natural Products
  3. Plants
  4. Caryophyllaceae
  5. Vaccaria segetalis (Neck.) Garcke

Vaccaria segetalis (Neck.) Garcke

Vaccaria segetalis (Neck.) Garcke (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-107245
    Segetalin B 164991-89-3 99.51%
    Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B significantly decreases bone loss, inhibits calcium and phosphorus loss, elevates ALP activity, upregulates Runx2, Osterix, and SIRT1, and downregulates Notch intracellular domain (NICD), acetyl-NICD, and hairy and enhancer of split 1 (Hes1) in ovariectomized rats. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP).
    Segetalin B
  • HY-N2589
    Isosaponarin 19416-87-6 99.59%
    Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin increases collagen synthesis, caused by up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production.
    Isosaponarin
  • HY-N5148
    Vaccarin E 2252345-81-4
    Vaccarin E is a natural C-glycosylflavone that could be isolated from V. hispanica.
    Vaccarin E