2. GPCR/G Protein Neuronal Signaling
  3. Neuropeptide Y Receptor
  4. Neuropeptide Y (13-36), amide, human

Neuropeptide Y (13-36), amide, human  (Synonyms: Neuropeptide Y (13-36), human)

Cat. No.: HY-P1480 Purity: 98.48%
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Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y2 receptor agonist.

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Neuropeptide Y (13-36), amide, human Chemical Structure

Neuropeptide Y (13-36), amide, human Chemical Structure

CAS No. : 122341-40-6

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Based on 1 publication(s) in Google Scholar

Neuropeptide Y (13-36), amide, human Related Antibodies

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Description

Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y2 receptor agonist[1].

IC50 & Target[2]

NPY Y2 receptor

 

In Vivo

Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].
Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into naïve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male ICR mice (age 4-7 weeks)[2]
Dosage: 50 ng/mouse
Administration: Intracerebroventricular injection
Result: Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.
Molecular Weight

3000.40

Formula

C134H207N41O36S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence Shortening

PAEDMARYYSALRHYINLITRQRY-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

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References
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Neuropeptide Y (13-36), amide, human Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neuropeptide Y (13-36), amide, human122341-40-6Neuropeptide Y (13-36), humanNeuropeptide Y ReceptorNPY receptoragonistsocial preferenceInhibitorinhibitorinhibit

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