2. One-stop Drug Screening
  3. Screening Libraries
  4. Bioactive Compound Series
  5. Disease Related Compound Libraries
  6. Endocrinology Compound Library
Endocrinology Compound Library

Cat. No.: HY-L047

The endocrine system is a chemical messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. Hormones are chemicals that serve to communicate between organs and tissues for physiological regulation and behavioral activities. Hormones affect distant cells by binding to specific receptor proteins in the target cell, resulting in a change in cell function.

The endocrine system is concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Irregulated hormone release, inappropriate response to signaling or lack of a gland can lead to endocrine disease.

MCE offers a unique collection of 913 endocrinology related compounds targeting varieties of hormone receptors such as thyroid hormone receptor, TSH receptor, GNRH receptor, adrenergic receptor, etc. MCE Endocrinology Compound Library is a useful tool for the discovery of endocrinology drugs.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +
Contact Us for Customization

Compound Screening Libraries

Download
Related Products
Recommendation

Top Publications Citing Use of MedChemExpress (MCE) Products

View More

Publications Citing Use of MedChemExpress (MCE) Products

  • Biological Activity
  • Product Details
  • Composition

Description & Advantages

•   A unique collection of 913 bioactive compounds which can be used in the research of endocrine regulation.

•   Targets include thyroid hormone receptor, TSH receptor, GNRH receptor, adrenergic receptor related signaling pathways.

•   A useful tool for the discovery of endocrinology drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 913 endocrinology compounds supplied as pre-dissolved Solutions or Solid
Solution: 899 compounds supplied in 10 mM solution, 12 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

CXCR (35)

CCR (34)

HIV (15)

GHSR (11)

COX (5)

CRFR (5)

PPAR (4)

CFTR (3)

FAK (3)

Wnt (3)

CaSR (2)

EGFR (2)

HCV (2)

ROCK (2)

Related Service
Recommendation
Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
  •  YES
Contact Us for Customization

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Container *

    Remarks

    Inquiry Information

    Product Name:
    Endocrinology Compound Library
    Cat. No.:
    HY-L047
    Quantity:
    MCE Japan Authorized Agent:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

    Request for SDF File

    Please fill out this form to request the SDF file. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

    Product Name

    		  

    Applicant Name *

    Email Address *

    		 

    Organization Name *

    Phone Number

    		     

    Remarks

    Request for SDF File

    We have received your request and will respond to you as soon as possible.