2. Cytoskeleton
  3. Integrin
  4. RGD Trifluoroacetate

RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

RGD Trifluoroacetate Chemical Structure

RGD Trifluoroacetate Chemical Structure

CAS No. : 2378808-45-6

Size Price Stock Quantity
5 mg USD 70 In-stock
10 mg USD 120 In-stock
25 mg USD 240 In-stock
50 mg USD 380 In-stock
100 mg USD 580 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 6 publication(s) in Google Scholar

Other Forms of RGD Trifluoroacetate:

  • RGD Get quote

RGD Trifluoroacetate Related Antibodies

Top Publications Citing Use of Products

View All Integrin Isoform Specific Products:

View All Isoforms
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

IC50 & Target

Integrin[1]
In Vitro

RGD Trifluoroacetate is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RGD Trifluoroacetate Related Antibodies
Molecular Weight

460.36

Formula

C14H23F3N6O8
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Gly-Asp
Sequence Shortening

RGD
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (271.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1722 mL 10.8611 mL 21.7221 mL
5 mM 0.4344 mL 2.1722 mL 4.3444 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (217.22 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.75%

COA (246 KB) RP-HPLC (184 KB) Elemental Analysis Report (106 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1722 mL 10.8611 mL 21.7221 mL 54.3053 mL
5 mM 0.4344 mL 2.1722 mL 4.3444 mL 10.8611 mL
10 mM 0.2172 mL 1.0861 mL 2.1722 mL 5.4305 mL
15 mM 0.1448 mL 0.7241 mL 1.4481 mL 3.6204 mL
20 mM 0.1086 mL 0.5431 mL 1.0861 mL 2.7153 mL
25 mM 0.0869 mL 0.4344 mL 0.8689 mL 2.1722 mL
30 mM 0.0724 mL 0.3620 mL 0.7241 mL 1.8102 mL
40 mM 0.0543 mL 0.2715 mL 0.5431 mL 1.3576 mL
50 mM 0.0434 mL 0.2172 mL 0.4344 mL 1.0861 mL
60 mM 0.0362 mL 0.1810 mL 0.3620 mL 0.9051 mL
80 mM 0.0272 mL 0.1358 mL 0.2715 mL 0.6788 mL
100 mM 0.0217 mL 0.1086 mL 0.2172 mL 0.5431 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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RGD Trifluoroacetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RGD2378808-45-6IntegrinInhibitorinhibitorinhibit

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