2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W020182
    α-Terpinene 99-86-5
    α-Terpinene (Terpilene) is a monoterpene found in the essential oils of a large variety of foods and aromatic plants such as Mentha piperita. α-Terpinene is active against Trypanosoma evansi and has the potential for trypanosomosis treatment. α-Terpinene has antioxidant and antifungal properties.
    α-Terpinene
  • HY-W129596
    Policresulen 101418-00-2
    Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability.
    Policresulen
  • HY-W324882
    Salinazid 495-84-1 99.91%
    Salinazid is an antituberculous compound.
    Salinazid
  • HY-17036
    Naphthoquine phosphate 173531-58-3 99.59%
    Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine.
    Naphthoquine phosphate
  • HY-17437
    Mefloquine 53230-10-7 99.96%
    Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research.
    Mefloquine
  • HY-44178
    Diethyl butylmalonate 133-08-4 99.79%
    Diethyl butylmalonate exhibits toxicity to T. pyriformis, with a log(IGC50-1) of 0.557.
    Diethyl butylmalonate
  • HY-B0914
    10-Undecenoic acid,98% (stabilized with TBC) 112-38-9 ≥98.0%
    10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa.
    10-Undecenoic acid,98% (stabilized with TBC)
  • HY-B0960
    Sulfabenzamide 127-71-9 99.68%
    Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative bacterial strains.
    Sulfabenzamide
  • HY-B1143
    Broxaldine 3684-46-6 99.50%
    Broxaldine (Brobenzoxaldine) is an antiprotozoal agent. Broxaldine inhibits Clostridium difficile with a MIC value of 4 µM, and has antifungal effects.
    Broxaldine
  • HY-B1267
    Sulfaguanidine 57-67-0 ≥98.0%
    Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
    Sulfaguanidine
  • HY-B1530
    Ammonium lactate (60% in water) 515-98-0
    Ammonium lactate is the ammonium salt of lactic acid, with mild anti-bacterial properties. Ammonium lactate can be used for the research of xerosis.
    Ammonium lactate (60% in water)
  • HY-B2004
    Thifluzamide 130000-40-7 98.36%
    Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields.
    Thifluzamide
  • HY-N0838
    Cephalotaxine 24316-19-6 ≥98.0%
    Cephalotaxlen ((-)-Cephalotaxine) is an alkaloid that can be isolated from Cephalotaxus fortunei, with antileukemic and antiviral activities. Cephalotaxlen has anti-ZIKV (Zika virus) activity.
    Cephalotaxine
  • HY-Y0532
    N-Chlorosuccinimide 128-09-6 ≥98.0%
    N-Chlorosuccinimide can enhance the antimicrobial effect of Benzalkonium chloride (HY-B2232) on biofilm Pseudomonas aeruginosa.
    N-Chlorosuccinimide
  • HY-164793
    TGFBR1-IN-2 733806-89-8
    TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis.
    TGFBR1-IN-2
  • HY-22055B
    AN-12-H5 intermediate-1 254882-14-9 ≥98.0%
    AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
    AN-12-H5 intermediate-1
  • HY-B0420A
    Moroxydine hydrochloride 3160-91-6 99.45%
    Moroxydine (ABOB) hydrochloride has multi-antiviral activities against DNA and RNA viruses including influenza symptoms, herpes simplex, varicellazoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride shows high anti-grass carp reovirus (GCRV) activity.
    Moroxydine hydrochloride
  • HY-Y0320R
    Dimethyl sulfoxide (Standard) 67-68-5 99.99%
    Dimethyl sulfoxide (Standard) is the analytical standard of Dimethyl sulfoxide. This product is intended for research and analytical applications. Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves both polar and nonpolar compounds. Dimethyl sulfoxide has anti-freezing and bacteriostatic properties.
    Dimethyl sulfoxide (Standard)
  • HY-131576A
    Thymidine 5′-diphosphate sodium 108322-12-9 ≥99.0%
    Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate.
    Thymidine 5′-diphosphate sodium
  • HY-W003943
    6-Hydroxypyridin-3-ylboronic acid 903899-13-8
    6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors.
    6-Hydroxypyridin-3-ylboronic acid
Cat. No. Product Name / Synonyms Application Reactivity