2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-148493
    MK-3402 2058151-78-1 99.96%
    MK-3402 (Compound303) is a metallo-beta-lactamase inhibitor, with IC50 values of 0.53, 0.25 and 0.169 nM against IMP-1, NDM-1, and VIM-1, respectively. MK-3402 can be used in bacterial research and shows a synergistic effect when used in combination with beta-lactam antibiotics.
    MK-3402
  • HY-15602B
    Ledipasvir D-tartrate 1502654-87-6 98.76%
    Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
    Ledipasvir D-tartrate
  • HY-160519
    Targocil-II 955918-74-8 98.92%
    Targocil-II (Compound 2) is an ABC transporter inhibitor with a IC50 value of 137 nM. Targocil-II prevents ATP hydrolysis by binding to allosteric sites of the TM domain. Targocil-II has (antibacterial) activity.
    Targocil-II
  • HY-17460A
    Garenoxacin Mesylate hydrate 223652-90-2 99.78%
    Garenoxacin (BMS284756) Mesylate hydrate is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms.
    Garenoxacin Mesylate hydrate
  • HY-B0215S
    Acetylcysteine-d3 131685-11-5
    Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.
    Acetylcysteine-d3
  • HY-B0712A
    Ceftriaxone sodium hydrate 104376-79-6 99.25%
    Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis.
    Ceftriaxone sodium hydrate
  • HY-B1596A
    Ceftizoxime sodium 68401-82-1 99.77%
    Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
    Ceftizoxime sodium
  • HY-B1894A
    Cefetamet pivoxil hydrochloride 111696-23-2 ≥98.0%
    Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.
    Cefetamet pivoxil hydrochloride
  • HY-N0113B
    Hordenine hydrochloride 6027-23-2 99.82%
    Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.
    Hordenine hydrochloride
  • HY-N12851
    4-OHE 2492-43-5
    4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by the peroxidation of omega-3 fats. 4-OHE has antibacterial activity.
    4-OHE
  • HY-U00092
    BAY-Y 3118 151213-16-0 99.22%
    BAY-Y 3118 is a new chlorofluoroquinolone with antimicrobial activity.
    BAY-Y 3118
  • HY-U00128
    PPA-904 30189-85-6 99.31%
    PPA-904 is a specific phenothiazine photosensitizer in photodynamic research (PDT) research, especially topical application for cutaneous leishmaniasis in vivo.
    PPA-904
  • HY-U00249
    Saperconazole 110588-57-3 99.35%
    Saperconazole (R66905) is a broad-spectrum antifungal triazole and has potent activity against Aspergillus with an MIC90 of 0.19 mg/L.
    Saperconazole
  • HY-17589AR
    Chloroquine (Standard) 54-05-7
    Chloroquine (Standard) is the analytical standard of Chloroquine. This product is intended for research and analytical applications. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM).
    Chloroquine (Standard)
  • HY-W001663
    4'-Hydroxy-3'-methylacetophenone 876-02-8 99.96%
    4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity.
    4'-Hydroxy-3'-methylacetophenone
  • HY-W004570
    5-Nitro-1,10-phenanthroline 4199-88-6 99.88%
    5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells.
    5-Nitro-1,10-phenanthroline
  • HY-W009722
    Sodium diethylcarbamodithioate trihydrate 20624-25-3 ≥98.0%
    Sodium diethylcarbamodithioate (Ditiocarb sodium) trihydrate is a copper reagent. The reaction with Cu2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer.
    Sodium diethylcarbamodithioate trihydrate
  • HY-W012267
    2-Bromo-2'-methoxyacetophenone 31949-21-0 ≥98.0%
    2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, that inhibits MurA in E. coli with an IC50 of 0.38 μM. 2-Bromo-2'-methoxyacetophenone can be used in antibacterial research for blocking bacterial cell wall synthesis.
    2-Bromo-2'-methoxyacetophenone
  • HY-W012634
    Benzothiazole 95-16-9 ≥98.0%
    Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent[1][2][3][4].
    Benzothiazole
  • HY-W014120
    Thianthrene 92-85-3 99.98%
    Thianthrene, a sulfur-containing heterocyclic compound, is a derivative of dithiin. Thianthrene can be used in the research of dermal infections, in which it interferes with enzyme and nucleic acid function.
    Thianthrene
Cat. No. Product Name / Synonyms Application Reactivity