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SPQ is being used to examine and measure membrane chloride transport mechanisms.

For research use only. We do not sell to patients.

SPQ Chemical Structure

SPQ Chemical Structure

CAS No. : 83907-40-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
50 mg USD 50 In-stock
100 mg USD 80 In-stock
250 mg USD 190 In-stock
500 mg USD 350 In-stock
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

SPQ is being used to examine and measure membrane chloride transport mechanisms.

Molecular Weight

281.33

Formula

C13H15NO4S
CAS No.
Appearance

Solid

Color

White to gray

Emission (Em)

443
Excitation (Ex)

344
SMILES

O=S(CCC[N+]1=C2C=CC(OC)=CC2=CC=C1)([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (88.86 mM; Need ultrasonic)

DMSO : 1 mg/mL (3.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5545 mL 17.7727 mL 35.5454 mL
5 mM 0.7109 mL 3.5545 mL 7.1091 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 10 mg/mL (35.55 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.52%

COA (251 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.5545 mL 17.7727 mL 35.5454 mL 88.8636 mL
H2O 5 mM 0.7109 mL 3.5545 mL 7.1091 mL 17.7727 mL
10 mM 0.3555 mL 1.7773 mL 3.5545 mL 8.8864 mL
15 mM 0.2370 mL 1.1848 mL 2.3697 mL 5.9242 mL
20 mM 0.1777 mL 0.8886 mL 1.7773 mL 4.4432 mL
25 mM 0.1422 mL 0.7109 mL 1.4218 mL 3.5545 mL
30 mM 0.1185 mL 0.5924 mL 1.1848 mL 2.9621 mL
40 mM 0.0889 mL 0.4443 mL 0.8886 mL 2.2216 mL
50 mM 0.0711 mL 0.3555 mL 0.7109 mL 1.7773 mL
60 mM 0.0592 mL 0.2962 mL 0.5924 mL 1.4811 mL
80 mM 0.0444 mL 0.2222 mL 0.4443 mL 1.1108 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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SPQ Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SPQ83907-40-8Fluorescent DyeInhibitorinhibitorinhibit

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