1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Sofosbuvir impurity D

Sofosbuvir impurity D is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

For research use only. We do not sell to patients.

Sofosbuvir impurity D Chemical Structure

Sofosbuvir impurity D Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Sofosbuvir impurity D is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

Molecular Weight

529.45

Formula

C22H29FN3O9P

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=[P@@](N[C@@H](C)C(OC(C)C)=O)(OC[C@H]1[C@H](O)[C@@](F)(C)[C@@H](N2C=CC(NC2=O)=O)O1)OC3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (94.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8888 mL 9.4438 mL 18.8875 mL
5 mM 0.3778 mL 1.8888 mL 3.7775 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8888 mL 9.4438 mL 18.8875 mL 47.2188 mL
5 mM 0.3778 mL 1.8888 mL 3.7775 mL 9.4438 mL
10 mM 0.1889 mL 0.9444 mL 1.8888 mL 4.7219 mL
15 mM 0.1259 mL 0.6296 mL 1.2592 mL 3.1479 mL
20 mM 0.0944 mL 0.4722 mL 0.9444 mL 2.3609 mL
25 mM 0.0756 mL 0.3778 mL 0.7555 mL 1.8888 mL
30 mM 0.0630 mL 0.3148 mL 0.6296 mL 1.5740 mL
40 mM 0.0472 mL 0.2361 mL 0.4722 mL 1.1805 mL
50 mM 0.0378 mL 0.1889 mL 0.3778 mL 0.9444 mL
60 mM 0.0315 mL 0.1574 mL 0.3148 mL 0.7870 mL
80 mM 0.0236 mL 0.1180 mL 0.2361 mL 0.5902 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Sofosbuvir impurity D Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sofosbuvir impurity D
Cat. No.:
HY-I0723
Quantity:
MCE Japan Authorized Agent: