2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Adrenergic Receptor
  5. Adrenergic Receptor Inhibitor

Adrenergic Receptor Inhibitor

Adrenergic Receptor Isoform Comparison

Adrenergic Receptor Inhibitors (207):

Cat. No. Product Name Effect Purity
  • HY-14539A
    Clozapine hydrochloride
    		Inhibitor
    Clozapine hydrochloride (HF 1854 hydrochloride) is an antipsychotic used for the research of schizophrenia. Clozapine hydrochloride has high affinity for a number of neuroreceptors. Clozapine hydrochloride is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine hydrochloride inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine hydrochloride is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM).
  • HY-122053
    Amidephrine hydrochloride
    		Inhibitor
    Amidephrine (hydrochloride) is an adrenergic receptor (AR) agonist. Amidephrine (hydrochloride) can be used in the research of neurological diseases.
  • HY-106554A
    Trimazosin hydrochloride hydrate
    		Inhibitor
    Trimazosin hydrochloride hydrate is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenergic receptor.
  • HY-B1392S
    Esmolol-d7 hydrochloride
    		Inhibitor
    Esmolol-d7 (hydrochloride) is the deuterium labeled Esmolol hydrochloride. Esmolol hydrochloride is a beta adrenergic receptor blocker[1][2].
  • HY-A0016S
    Dronedarone-d6 hydrochloride
    		Inhibitor
    Dronedarone-d6 (hydrochloride) is the deuterium labeled Dronedarone. Dronedarone hydrochloride, a derivative of Amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone hydrochloride is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone hydrochloride is a substrate for and a moderate inhibitor of CYP3A4[1][2][3][4].
  • HY-U00313
    Tropodifene
    		Inhibitor
    Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.
  • HY-U00244
    Benzquinamide
    		Inhibitor
    Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively.