2. Signaling Pathways
  3. Neuronal Signaling
  4. Amyloid-β
  5. Amyloid-β Ligand

Amyloid-β Ligand

Amyloid-β Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-153898
    rTRD01
    		Ligand
    rTRD01 is a TDP-43 ligand that binds to TDP-43’s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102–269). rTRD01 partially disrupts TDP-43’s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases.
  • HY-163575
    TDP-43-IN-2
    		Ligand
    TDP-43-IN-2 (compound 17) is a TDP-43 inhibitor, and can be used for study of neurodegenerative disease.