2. Signaling Pathways
  3. Neuronal Signaling
  4. Amyloid-β
  5. Amyloid-β Chemical

Amyloid-β Chemical

Amyloid-β Chemicals (5):

Cat. No. Product Name Effect Purity
  • HY-103240
    Methoxy-X04
    		Chemical 98.46%
    Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity.
  • HY-139516
    AZD4694 Precursor
    		Chemical 98.07%
    AZD4694 Precursor (AZ13040214) is the precursor of [18F] AZD4694 for the synthesis of [18F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques.
  • HY-D1684
    DCDAPH
    		Chemical
    DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λex/λem=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo.
  • HY-P3793
    Amyloid β-Protein (33-42) (TFA)
    		Chemical
    Amyloid β-Protein (33-42) TFA is the residues 33-42 fragment of the β-amyloid protein. Amyloid β-Protein (33-42) TFA inhibits Aβ42-induced toxicity.
  • HY-P4788
    Acetyl-Amyloid β-Protein (1-6) amide
    		Chemical
    Acetyl-Amyloid β-Protein (1-6) amide is a hexapeptide that contains a potential copper(II) binding site. Acetyl-Amyloid β-Protein (1-6) amide can be used for research of Alzheimer's disease and related disorders.