2. Signaling Pathways
  3. Apoptosis
  4. Apoptosis
  5. Apoptosis Degrader

Apoptosis Degrader

Apoptosis Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-13224
    AZD4877
    		Degrader 98.15%
    AZD4877 is another isostere to Ispinesib (HY-50759)and also a kinesin spindle protein (Eg5) inhibitor with IC50 of 2 nM.AZD4877 arrests cell mitosis, leads to the formation of the monopolar spindle phenotype and induces apoptosis. AZD4877 inhibits circulating peripheral blood mononuclear cells (PBMCs) and has anti-cancer activity.