2. Signaling Pathways
  3. Autophagy
  4. Autophagy
  5. Autophagy Agonist

Autophagy Agonist

Autophagy Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-P10343
    Soybean peptide QRPR
    		Agonist
    Soybean peptide QRPR is an agonist of Autophagy. Soybean peptide QRPR activates cellular autophagy by upregulating the expression and activity of PIK3, AKT, and mTOR. Soybean peptide QRPR can reduce the inflammatory response.
  • HY-170992
    Autophagy agonist-1
    		Agonist
    Autophagy agonist-1 (compound 22) is an Autophagy agonist. Autophagy agonist-1 exhibits significant anticancer activity against HepG2 cells and normal cells with IC50s of 8.8 μM and > 50 μM. Autophagy agonist-1 induces G1/S phase cell cycle arrest and inhibits CDK4 and CyclinD1 expression while upregulating P21. Autophagy agonist-1 promotes the accumulation of autophagosomes and the proteins LC3 and PINK1, enhancing autophagy and mitophagy in HepG2 cells.