2. Signaling Pathways
  3. GPCR/G Protein
  4. CaSR
  5. CaSR Control

CaSR Control

CaSR Control (1):

Cat. No. Product Name Effect Purity
  • HY-103320B
    (1R,2R)-Calhex 231 hydrochloride
    		Control 99.07%
    (1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment.