2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. Calcium Channel
  5. Calcium Channel Modulator

Calcium Channel Modulator

Calcium Channel Isoform Comparison

Calcium Channel Modulators (24):

Cat. No. Product Name Effect Purity
  • HY-120411
    Sadopine
    		Modulator
    Sadopine is an allosteric modulator for dihydropyridine receptor ((-)Sadopine as positive allosteric modulator and (+)Sadopine as negative allosteric modulator). Sadopine interacts with dihydropyridine (DHP)-sensitive L-type calcium channels.
  • HY-149779
    RyR2 stabilizer-1
    		Modulator
    RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM for RyR2 and 383 nM for SERCA2. RyR2 stabilizer-1 inhibits Ca2+ leakage from the SR RyR2 while promoting SERCA2 to pump Ca2+ back to SR, which make RyR2 stabilizer-1 possible to prevent cardiac arrhythmias.
  • HY-P0268
    Myomodulin
    		Modulator
    Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.
  • HY-U00135
    Calcium channel-modulator-1
    		Modulator 98.77%
    Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.