2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Carbonic Anhydrase
  5. CA Ⅱ Isoform

CA Ⅱ

 
Cat. No. Product Name Effect Purity
  • HY-B0109S
    Dorzolamide-d5
    		Inhibitor
    Dorzolamide-d5 is the deuterium labeled Dorzolamide. Dorzolamide (L671152) is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity[1][2].
  • HY-125375
    L-662583
    		Inhibitor
    L-662583 is a locally active carbonic anhydrase II inhibitor with an IC50 value of 0.7 nM.
  • HY-163753
    Carbonic anhydrase inhibitor 25
    		Inhibitor
    Carbonic anhydrase inhibitor 25 (compound 6a) is a potent carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 25 shows inhibition for hCA I and hCA II receptor.
  • HY-157321
    hCAI/II-IN-7
    		Inhibitor
    hCAI/II-IN-7 (compound 1F) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 23 nM, 44 nM and 20.57 µM for hCA-I, hCA-II and bovine CA, respectively.
  • HY-172178
    hCAIX/XII-IN-14
    		Inhibitor
    hCAIX/XII-IN-14 (Compound 1i) is an hCAIX/XII inhibitor, with Ki values of hCAII, hCAIX, and hCAXII for 9.4 nM, 5.6 nM, and 6.3 nM, respectively.
  • HY-162226
    Carbonic anhydrase inhibitor 19
    		Inhibitor
    Carbonic anhydrase inhibitor 19 (compound 26a) inhibits the Glaucoma related isoforms hCA II and hCA XII with Kis of 9.4 nM and 6.7 nM, respectively. Carbonic anhydrase inhibitor 19 reveals an intraocular pressure (IOP) lowering effect.
Cat. No. Product Name / Synonyms Species Source