1. Signaling Pathways
  2. Apoptosis
  3. Caspase
  4. Caspase 2 Isoform
  5. Caspase 2 Activator

Caspase 2 Activator

Caspase 2 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-B1193
    Terfenadine
    Activator 99.91%
    Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.